Dihexa

Dihexa Research Material — Buy Dihexa (N-Hexanoic-Tyr-Ile-(6)Aminohexanoic Amide) (≥97% Purity)

Dihexa is a small molecule derived from the N-terminus of Angiotensin IV, developed to activate the hepatocyte growth factor (HGF)/c-Met signaling pathway. It is among the most potent synaptogenic compounds identified in preclinical neuroscience literature, studied at amounts many orders of magnitude lower than earlier angiotensin IV-derived candidates.

Mechanism of Action

Dihexa activates the HGF/c-Met receptor signaling pathway, a mechanism strongly implicated in synaptogenesis (formation of new synaptic connections) and neuroplasticity. This pathway is a major research focus in models of cognitive decline, neurodegeneration, and memory consolidation.

Research Applications

• Synaptogenesis and neuroplasticity research
• HGF/c-Met signaling pathway studies
• Cognitive decline and neurodegeneration models
• Memory formation and consolidation research
• Comparative studies against other neurotrophic compounds

Specifications

• Chemical Name: Dihexa (N-Hexanoic-Tyr-Ile-(6)Aminohexanoic Amide)
• CAS Number: 1401708-83-5
• Molecular Formula: C₂₁H₃₂N₂O₄
• Molecular Weight: 376.5 Da
• Sequence: Derived from the N-terminus of Angiotensin IV — small molecule, not a standard amino acid chain
• Purity: ≥97% (HPLC verified)
• Form: Lyophilized powder
• Available Sizes: 5mg, 10mg

Storage & Handling

Store lyophilized Dihexa at −20°C, in a sealed container protected from light and moisture. All handling should be performed under standard laboratory conditions by trained research personnel.

For in-vitro laboratory research use only. Not for human or animal consumption. Not a drug, supplement, or medicinal product.