Semax

Semax Research Material — Buy Semax (≥97% Purity)

Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, developed to retain the neurotropic properties of ACTH while eliminating its hormonal activity. It has an extensive preclinical research history in cognitive and neuroprotective pharmacology, particularly in models of cerebral ischemia and cognitive decline.

Mechanism of Action

Semax modulates expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), and influences dopaminergic and serotonergic neurotransmission. Its neurotrophic signaling profile is central to its research use in models of neuroprotection, synaptic plasticity, and cognitive performance.

Research Applications

• Cognitive function and memory formation research
• BDNF/NGF expression and neurotrophic signaling studies
• Neuroprotection and cerebral ischemia models
• Dopaminergic and serotonergic pathway research
• Stress and HPA axis modulation studies

Specifications

• Chemical Name: Semax
• CAS Number: 80714-61-0
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: 813.9 Da
• Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
• Purity: ≥97% (HPLC verified)
• Form: Lyophilized powder
• Available Sizes: 5mg, 10mg

Storage & Handling

Store lyophilized Semax at −20°C, protected from light and moisture. Once reconstituted with bacteriostatic water, store at 4°C and use within 28 days. All handling should be performed under sterile laboratory conditions by trained research personnel.

For in-vitro laboratory research use only. Not for human or animal consumption. Not a drug, supplement, or medicinal product.