TB-500 Research Material — Buy Thymosin Beta-4 Analog (≥97% Purity)
TB-500 (CAS 77591-33-4) is a synthetic analog of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein involved in actin sequestration and cytoskeletal organization. Representing one of the most active fragments of Tβ4, TB-500 is a high-priority research compound studied for its roles in tissue repair, regenerative biology, and vascular remodeling — and is consistently among the most purchased research materials in the research community.
Mechanism of Action
TB-500 promotes cell migration and proliferation primarily by upregulating actin dynamics. It binds G-actin monomers, reducing their sequestration and facilitating cytoskeletal remodeling. Research models show upregulation of integrin receptors, reduction of inflammatory cytokines, increased angiogenesis, and modulation of matrix metalloproteinase (MMP) activity — collectively making it a versatile compound in regenerative biology research.
Research Applications
- Wound healing and dermal tissue repair models
- Cardiac and skeletal muscle injury research
- Angiogenesis and vascular biology studies
- Inflammatory pathway and cytokine modulation
- Hair follicle biology and scalp research models
Specifications
- Chemical Name: Thymosin Beta-4 Fragment (TB-500)
- CAS Number: 77591-33-4
- Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
- Molecular Weight: ~4,963 Da
- Purity: ≥97% (HPLC verified)
- Form: Lyophilized powder
- Available Sizes: 5mg, 10mg
Storage & Handling
Store lyophilized TB-500 at −20°C, away from light and humidity. Reconstitute with bacteriostatic water and store reconstituted solution at 4°C for up to 28 days. Handle under sterile conditions by qualified laboratory personnel only.
For in-vitro laboratory research use only. Not for human or animal consumption. Not a drug, supplement, or medicinal product.
