Ipamorelin

Ipamorelin Research Material — Buy Ipamorelin (≥97% Purity)

Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue, functioning as a ghrelin receptor (GHS-R1a) agonist. It is distinguished in preclinical literature by its high selectivity for GH release with minimal impact on cortisol, prolactin, or ACTH — a property that has made it one of the most studied secretagogues for isolating GH-specific research outcomes.

Mechanism of Action

Ipamorelin binds the ghrelin receptor (GHS-R1a) on pituitary somatotrophs, triggering GH release through a signaling pathway distinct from and complementary to GHRH agonists like CJC-1295. Its selectivity profile — minimal off-target activation of the HPA axis — allows researchers to isolate GH-specific effects without the confounding cortisol or prolactin elevation seen with older-generation GHRPs (e.g. GHRP-6).

Research Applications

• Selective GH secretagogue and ghrelin receptor pharmacology studies
• Body composition and lean mass research
• Sleep and recovery physiology models
• Aging pituitary function and GH decline research
• Combination protocols with GHRH analogs (e.g. CJC-1295) for synergistic GH pulse studies

Specifications

• Chemical Name: Ipamorelin
• CAS Number: 170851-70-4
• Molecular Formula: C₃₈H₄₉N₉O₅
• Molecular Weight: 711.85 Da
• Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
• Purity: ≥97% (HPLC verified)
• Form: Lyophilized powder
• Available Sizes: 5mg, 10mg

Storage & Handling

Store lyophilized Ipamorelin at −20°C, protected from light and moisture. Once reconstituted with bacteriostatic water, store at 4°C and use within 28 days. All handling should be performed under sterile laboratory conditions by trained research personnel.

For in-vitro laboratory research use only. Not for human or animal consumption. Not a drug, supplement, or medicinal product.